Franko Klisović is born in Šibenik, where he finished his elementary and higher musical education at the Ivan Lukačić music school in the class of prof. Gordana Pavić, department of piano and musical theory. Whilst living in his home town he also worked as an organist at the cathedral of St. James in Šibenik. After graduating from high school he enrolls to study conducting at the Music Academy in Zagreb, where he is currently in his final year of studies in the class of mo. Tomislav Fačini. He had his conducting debut in March 2019 conducting the performance of W. A. Mozart's opera Cosi fan tutte and in the same year he also conducted the premiere of the musical Stribor’s Forest in the Zagreb City Theatre “Comedy“. In May 2021 as an assistent conductor, he conducted the performance of J. Massenet’s opera Cendrillon.

At the end of 2015 he starts his vocal studies and after only three months gets the role of Ottone in G. F. Händel's opera Agrippina with which he debuts in April 2016 at the Croatian National Theater in Zagreb. Not long after that, alongside his conducting studies, he enrolls to study singing at the Music academy in Zagreb in the class of prof. Martina Gojčeta – Silić. This season he will graduate as Smeton in Donizetti's Anna Bolena at the Croatian National Theater in Rijeka.

In February 2017, being called by the Qatar Philharmonic Orchestra, he performed in Doha at the Katara Opera House. He had his debut at the Croatian National Theater Ivan pl. Zajc in Rijeka, Croatia in the role of The Spirit in H. Purcell's opera Dido and Aeneas but also embodies the role of Aeneas and The Sorceress at the music festivals Musica appassionata and Korkyra baroque festival. In the 2020/2021 season he was Nireno in the production of G. F. Händel’s Giulio Cesare in Egitto in Rijeka and with the same production he performed at the Savonlinna Opera Festival 2022 in Finland. In February 2023, he was engaged as Ulisse in the production of Corselli’s Achille in Sciro in the Teatro Real in Madrid. Upcoming roles are his Germany debut as Ottone in L’Incoronazione di Poppea at Bühnen Wuppertal in April 2023 and the role of Mars in La Concordia de Pianeti with Hudobnifestival Znojmo in February and July 2023 as well as the entire next season at the Heidelberg Theater in Germany.

He has won numerous awards at the internarional vocal competitions like: 3rd prize and the audience prize at the 4th international vocal competition Premiere Opera Fundation (NY, USA, 2020); 1st prize at the Tullio Serafin singing competition (Vicenza, IT, 2021) and the role of Farnace in Mozart’s Mitridate, re` di Ponto, with which he had made his debut at the Teatro Olimpico in September 2021; 2nd prize at the 27th Riccardo Zandonai competition for young opera singers (Riva del Garda, IT, 2021); 2nd prize and the award for the most beautifully performed song Ružičky at the 24th singing competition Mikulaš Schneider - Trnavsky (Trnava, SK, 2021); 2nd prize in the opera section and 1st prize in the sacred music section at the 4th international vocal competition San Colombano (Piacenza, IT, 2021). He is also one of the winners of the online round of the Aria Borealis competition (Bodø,NO,2022) and winner of the Mahler prize at the Gabriela Beñačková competition (Jhilava, CZ, 2022).

In addition to operas, he often performs as an oratorio and concert soloist (previous engagements include B. Galuppi’s La caduta di Adamo and Dixit Dominus, C. Monteverdi’s Vespro della Beata Vergine, G. F. Händel’s Messiah and Il trionfo del Tempo e del Disinganno, M. A. Charpentier’s Te Deum and Messe a` 8 voix, G. B. Pergolesi’s Stabat Mater, A. Vivaldi’s Gloria, J. S. Bach’s Johannes, Matthäus, Markus Passion and Magnificat, Carl Orff’s Carmina Burana alongside the renowned soprano Sumi Jo, L. Bernstein’s Chichester Psalms, A. Bruckner’s Te Deum, etc.) Since 2015/16 he performs regularly with the Antiphonus vocal ensemble, with the Croatian Radiotelevision choir and also is permanent performer of Croatian Baroque Ensemble (HRBA). He works with well-known conductors such as Marc Korovich, Ville Matvejeff, Laurence Cummings, Aapo Häkkinen, Luca Oberti, Albrecht Hansjörg, Hervè Niquet, Philipp von Steinaecker, Richard Rosemberg and others.